Development of Compartment Models of Epileptic Spike-wave Discharges
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منابع مشابه
Sleep deprivation and spike-wave discharges in epileptic rats.
The effects of sleep deprivation were studied on the occurrence of spike-wave discharges in the electroencephalogram of rats of the epileptic WAG/Rij strain, a model for absence epilepsy. This was done before, during and after a period of 12 hours of near total sleep deprivation. A substantial increase in the number of spike-wave discharges was found during the first 4 hours of the deprivation ...
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The risk of neurological diseases increases with age. In WAG/Rij rat model of absence epilepsy, the incidence of epileptic spike-wave discharges is known to be elevated with age. Considering close relationship between epileptic spike-wave discharges and physiologic sleep spindles, it was assumed that age-dependent increase of epileptic activity may affect time-frequency characteristics of sleep...
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Sir, We read with great interest the paper by Siniatchkin et al. (2010), in which they report the results of electroencephalogram (EEG) combined with functional MRI studies performed in children with epileptic encephalopathies with continuous spike-waves during sleep (CSWS). This paper undoubtedly brings novel and valuable data on the pathophysiology of epileptic encephalopathies with CSWS, poi...
متن کاملTime-frequency characteristics and dynamics of sleep spindles in WAG/Rij rats with absence epilepsy.
In rat models of absence epilepsy, epileptic spike-wave discharges appeared in EEG spontaneously, and the incidence of epileptic activity increases with age. Spike-wave discharges and sleep spindles are known to share common thalamo-cortical mechanism, suggesting that absence seizures might affect some intrinsic properties of sleep spindles. This paper examines time-frequency EEG characteristic...
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The combining of electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) is a unique noninvasive method for investigating the brain regions involved at the time of epileptic discharges. The neuronal discharges taking place during an interictal spike or spike-wave burst result in an increase in metabolism and blood flow, which is reflected in the blood oxygen-level dependen...
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